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一项比较氟比洛芬与对乙酰氨基酚治疗原发性痛经的双盲交叉研究报告。

Report of a double-blind crossover study to compare flurbiprofen with paracetamol in the treatment of primary dysmenorrhoea.

作者信息

Frank G J, Kefford R H

出版信息

J Int Med Res. 1983;11 Suppl 2:6-10.

PMID:6347755
Abstract

Thirty-one patients suffering from primary dysmenorrhoea completed a double-blind crossover study which demonstrated flurbiprofen (100 mg three times a day) to be significantly more effective than paracetamol (1 g three The study revealed an explicit patient preference for flurbiprofen. The incidence of side-effect was low for both treatments though one patient was withdrawn because of lack of efficacy and side-effects while taking paracetamol.

摘要

31名原发性痛经患者完成了一项双盲交叉研究,该研究表明氟比洛芬(每日三次,每次100毫克)比扑热息痛(每日三次,每次1克)显著更有效。该研究显示患者明确更倾向于氟比洛芬。两种治疗的副作用发生率都很低,不过有一名患者在服用扑热息痛时因缺乏疗效和出现副作用而退出研究。

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