Miyauchi Y, Nishimori M, Asano E, Sakaguchi Z, Ohara K, Okamoto T
Jpn J Antibiot. 1983 Apr;36(4):855-61.
T-1982 (cefbuperazone) was given intravenously to 21 children with the following acute bacterial infections; 13 cases of bronchopneumonia, 2 cases of urinary tract infection, 1 case of subcutaneous abscess, 1 case of cervical purulent lymphadenitis and acute tonsillitis, and 4 cases of acute bronchitis. Clinical effectiveness was obtained in 20 cases out of 21 cases and bacteriological effectiveness in 7 cases out of 8 cases. As for the side effects, 1 patient had asymptomatic eosinophilia, but no other laboratory abnormalities were observed. Above results suggest that T-1982 is a useful antibiotic for treating pediatric patients with various kinds of bacterial infections.
将T - 1982（头孢布宗）静脉注射给21名患有以下急性细菌感染的儿童；13例支气管肺炎、2例尿路感染、1例皮下脓肿、1例颈部脓性淋巴结炎和急性扁桃体炎以及4例急性支气管炎。21例中有20例获得临床疗效，8例中有7例获得细菌学疗效。至于副作用，1例患者出现无症状嗜酸性粒细胞增多，但未观察到其他实验室异常。上述结果表明，T - 1982是治疗患有各种细菌感染的儿科患者的一种有用抗生素。
