Kobashi H, Miyauchi Y, Nishioka A, Miyamoto N, Ohara K, Okamoto T
Jpn J Antibiot. 1985 Mar;38(3):759-65.
Cefminox (CMNX, MT-141) was given intravenously to 20 children with the following acute bacterial infections; 10 cases of bronchopneumonia, 4 cases of urinary tract infection, 2 cases of staphylococcal scalded skin syndrome, each 1 case of acute pharyngitis, acute tonsillitis, purulent cervical lymphadenitis and acute tonsillitis, and pleuritis. Good clinical responses were obtained in 18 patients out of 20 patients and bacteriological effectiveness in 13 strains out of 14 strains. No side effect was observed except for 1 case with diarrhea and 1 case with slight elevation of GOT and GPT. From the above clinical results, it is apparent that CMNX is a useful antibiotic for treating pediatric patients with various kinds of bacterial infections.
头孢米诺(CMNX,MT - 141)静脉注射给药于20例患有以下急性细菌感染的儿童;支气管肺炎10例、尿路感染4例、葡萄球菌烫伤样皮肤综合征2例、急性咽炎、急性扁桃体炎、化脓性颈淋巴结炎、急性扁桃体炎及胸膜炎各1例。20例患者中有18例临床反应良好,14株菌株中有13株细菌学疗效良好。除1例腹泻和1例谷草转氨酶(GOT)及谷丙转氨酶(GPT)轻度升高外,未观察到副作用。从上述临床结果来看,显然头孢米诺是治疗患有各种细菌感染的儿科患者的一种有用抗生素。