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伯杰肾病:组织学模式、血压与肾素之间的关系

Berger's nephropathy: relationship between histological pattern, blood pressure and renin.

作者信息

Degli Esposti E, Zucchelli P, Chiarini C, Santoro A, Sturani A, Zuccalà A, Cagnoli L, Donini U, Mandreoli M, Pasquali S

出版信息

Proc Eur Dial Transplant Assoc. 1983;19:696-700.

PMID:6348761
Abstract

Vascular damage (VD), glomerular sclerosis (GS), renin (PRA) and blood pressure were assessed in 50 patients with Berger's nephropathy. GS was present in 5/15 patients without VD and affected more than 15 per cent of glomeruli in seven patients with minimal VD. Nine out of 19 patients with GS were normotensive. VD was present in 35 patients: 16 were hypertensive and 19 normotensive. Therefore hypertension is not the only mechanism responsible for VD. In the seven normotensive patients with high PRA, GS was not present while VD was absent or minimal.

摘要

对50例伯杰氏肾病患者的血管损伤(VD)、肾小球硬化(GS)、肾素(PRA)和血压进行了评估。15例无VD的患者中有5例存在GS,7例轻度VD患者中超过15%的肾小球受到影响。19例GS患者中有9例血压正常。35例患者存在VD:16例高血压,19例血压正常。因此,高血压不是导致VD的唯一机制。在7例PRA高的血压正常患者中,不存在GS,VD不存在或很轻微。

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