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重症肾小球肾炎的血浆置换——谁能获益?

Plasma exchange in severe glomerulonephritis--who benefits?

作者信息

Swainson C P, Winney R J, Urbaniak S J, Robson J S

出版信息

Proc Eur Dial Transplant Assoc. 1983;19:732-7.

PMID:6348764
Abstract

Plasma exchange (PE) and immunosuppression was used in the treatment of 17 patients with severe glomerulonephritis and 17 acute rejections in transplant recipients. No response occurred in crescentic nephritis with anuria; a temporary improvement occurred in other nephritis patients but half of these relapsed on immunosuppression alone. Seven rejection episodes responded. Responses always occurred promptly and prolonged PE did not improve the results. Histology, serum complement or immune complex results did not predict a successful outcome.

摘要

血浆置换(PE)和免疫抑制疗法用于治疗17例重症肾小球肾炎患者以及17例移植受者的急性排斥反应。无尿的新月体性肾炎患者无反应;其他肾炎患者出现暂时改善,但其中一半仅靠免疫抑制治疗就复发了。七次排斥反应发作有反应。反应总是迅速出现,延长血浆置换并未改善结果。组织学、血清补体或免疫复合物结果无法预测成功的结果。

相似文献

1
Plasma exchange in severe glomerulonephritis--who benefits?重症肾小球肾炎的血浆置换——谁能获益?
Proc Eur Dial Transplant Assoc. 1983;19:732-7.
2
Still a role for plasma exchange in rapidly progressive glomerulonephritis?血浆置换在快速进展性肾小球肾炎中仍有作用吗?
J Nephrol. 1997 Jan-Feb;10(1):7-13.
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Clinical and morphological aspects of the management of crescentic anti-glomerular basement membrane antibody (anti-GBM) nephritis/Goodpasture's syndrome.新月体性抗肾小球基底膜抗体(抗GBM)肾炎/肺出血肾炎综合征治疗的临床与形态学方面
Q J Med. 1985 Jan;54(213):75-89.
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[Plasma exchange in rapidly progressive glomerulonephritis (author's transl)].
Dtsch Med Wochenschr. 1981 Nov 27;106(48):1616-20. doi: 10.1055/s-2008-1070565.
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[Plasma exchange in kidney diseases].
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Role of plasma exchange in renal disease.
J CANNT. 1991 Summer;1(3):18-21.
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Therapeutic plasma exchange (TPE) as a new therapy option on the Amicus.治疗性血浆置换(TPE)作为一种在Amicus上的新治疗选择。
Transfus Apher Sci. 2013 Apr;48(2):179. doi: 10.1016/j.transci.2013.02.026. Epub 2013 Mar 19.
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Plasma exchange in the treatment of rapidly progressive glomerulonephritis.血浆置换治疗急进性肾小球肾炎
Contrib Nephrol. 2013;181:240-7. doi: 10.1159/000348632. Epub 2013 May 8.
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Clinical trial of plasma exchange with a membrane filter in treatment of crescentic glomerulonephritis.使用膜滤器进行血浆置换治疗新月体性肾小球肾炎的临床试验
Clin Nephrol. 1980 Aug;14(2):60-5.
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Clin Nephrol. 1973 Jan-Feb;1(1):40-5.

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