Scholten T, Fritsch W P, Hagenmüller F, Classen M, Knop P, Hausamen T U, Lingenberg G, Portocarrero G, Safrany L, Seifert E, Zeus U, Stadelmann O
Z Gastroenterol. 1983 May;21(5):212-9.
63 inpatients with duodenal ulcer disease were treated with either depot-secretin or placebo. Two different secretin-regimens were used. In group I 18 patients were given secretin twice daily. 11 ulcers from a total of 19 ulcers healed within 3 weeks. In group II 23 patients were given secretin once daily. 21 out of 28 ulcers healed within 3 weeks. In the placebo-treated group 24 ulcers were observed in 22 patients. Of these 15 healed within 3 weeks. There was no statistical difference in the healing rate between the 3 groups. However, depot-secretin significantly improved typical symptoms. Analgetics were used less frequently. Serious side effects did not occur.
