Karesh J W, Nirankari V S
Am J Ophthalmol. 1983 Aug;96(2):160-4. doi: 10.1016/s0002-9394(14)77783-9.
We conducted a retrospective analysis of 80 eyes that underwent penetrating keratoplasties to determine the factors associated with early (less than three months) and late (more than three months) postoperative increases in intraocular pressure. The patients ranged in age from 14 to 91 years (mean age, 58.5 years). The 56 patients with aphakic eyes had a mean age of 64 years and the 24 patients whose eyes had lenses had a mean age of 48 years. In the 17 eyes with preoperative glaucoma, the intraocular pressure was controlled with medication (mean intraocular pressure, 17.6 mm Hg; range, 10 to 21 mm Hg). The follow-up periods ranged from 12 to 26 months (mean, 22 months). Of the 80 eyes, 25 had early increases in intraocular pressure and 23 had late increases. Twenty eyes showed increases during both periods. Of the 17 eyes with preoperative glaucoma, 14 had early increases and 15 had late increases (P less than .001). Of the 57 aphakic eyes, 24 had early increases (P less than .001) and 21 had late increases (P less than .025). Other factors (whether vitrectomy was done, suture technique, and graft size) were not statistically significant.
我们对80只接受穿透性角膜移植术的眼睛进行了回顾性分析，以确定与术后早期（少于三个月）和晚期（超过三个月）眼压升高相关的因素。患者年龄在14岁至91岁之间（平均年龄58.5岁）。56只无晶状体眼的患者平均年龄为64岁，24只眼有晶状体的患者平均年龄为48岁。在17只术前患有青光眼的眼中，眼压通过药物控制（平均眼压17.6毫米汞柱；范围10至21毫米汞柱）。随访时间为12至26个月（平均22个月）。在这80只眼中，25只眼压早期升高，23只眼压晚期升高。20只眼在两个时期均出现眼压升高。在17只术前患有青光眼的眼中，14只眼压早期升高，15只眼压晚期升高（P<0.001）。在57只无晶状体眼中，24只眼压早期升高（P<0.001），21只眼压晚期升高（P<0.025）。其他因素（是否进行玻璃体切除术、缝合技术和植片大小）无统计学意义。
