Givental' N I, Krasil'nikova O A, Osmanov S K, Bogdanova L F, Vorob'eva L S
Antibiotiki. 1983 May;28(5):325-31.
Sensitivity of 167 strains of beta-hemolytic streptococci of group A was studied with the method of serial dilutions on a solid agar medium for cultivation of streptococci. The medium was developed at the I. I. Mechnikov Research Institute of Vaccines and Sera. It does not require addition of blood or serum. The strains were found to be highly sensitive to penicillin, cephalothin and erythromycin. The number of the strains resistant to tetracycline, streptomycin, gentamycin, levomycetin (chloramphenicol) and ristomycin amounted to 51, 36, 23, 1.8 and 1.8 per cent, respectively. One of the strains (0.6 per cent) was resistant to lincomycin. Strains with multiple resistance were isolated. The necessity of regular control of distribution of antibiotic resistance among staphylococci is indicated.
采用在链球菌固体琼脂培养基上连续稀释的方法，对167株A组β溶血性链球菌的敏感性进行了研究。该培养基由I. I. 梅契尼科夫疫苗和血清研究所研制。它无需添加血液或血清。发现这些菌株对青霉素、头孢噻吩和红霉素高度敏感。对四环素、链霉素、庆大霉素、氯霉素和瑞斯托霉素耐药的菌株数量分别为51%、36%、23%、1.8%和1.8%。其中一株菌株（0.6%）对林可霉素耐药。分离出了多重耐药菌株。指出有必要定期监测葡萄球菌中抗生素耐药性的分布情况。
