Givental' N I, Krasil'nikova O A, Bogdanova L F, Vorob'eva L S, Labinskaia A S
Antibiotiki. 1984 Dec;29(12):917-21.
The MICs and MBCs (minimum bactericidal concentration) of 6 antibiotics (benzylpenicillin, oxacillin, cephalothin, ristomycin, erythromycin and lincomycin) for 50 strains of group A streptococci were determined with serial dilutions in a liquid medium (the medium for isolation of streptococci of the I. I. Mechnikov Moscow Research Institute of Vaccines and Sera) followed by volumetric platings on a solid medium (the same medium supplemented with 1.5 per cent agar). The results are discussed in relation to the problem of Streptococci tolerance to the bactericidal effect of the antibiotics.
采用在液体培养基（莫斯科伊·伊·梅奇尼科夫疫苗和血清研究所分离链球菌所用的培养基）中进行连续稀释，随后在固体培养基（添加1.5%琼脂的相同培养基）上进行定量平板接种的方法，测定了6种抗生素（苄青霉素、苯唑西林、头孢噻吩、瑞斯托菌素、红霉素和林可霉素）对50株A组链球菌的最低抑菌浓度（MIC）和最低杀菌浓度（MBC）。结合链球菌对抗生素杀菌作用耐受性的问题对结果进行了讨论。
