[Effect of LH releasing hormone on the state of gametes and the maturation of follicular oocytes in vitro].

Ovulation, gametogenesis and maturation of rat follicular oocytes were examined in vitro under the effect of single and repeated injections of LH-RF. It was shown that LH-RF injection led to incomplete ovulation and to alteration of the heterogeneity of the gametes as regards the degree of maturation and the number of the degenerating forms. At the same time it did not produce any substantial effect on the rate of chromosomal abnormalities. The pattern of maturation of follicular oocytes from rats given LH-RH attests to the enhancement of atresia in the ovaries.