Ashcroft J, Pomeroy N P
J Hyg (Lond). 1983 Aug;91(1):81-91. doi: 10.1017/s002217240006006x.
Experiments have been performed to simulate accidents which may occur during large-scale production of micro-organisms. Four types of accident, which were considered to be the most likely to result in the greatest hazard to health, were simulated using a bacterial model. The accidents were all concerned with faults occurring in the operation of the microbial fermenter. Gross contamination of surfaces occurred in all experiments, but only three types of accident produced a measurable aerosol.
已开展实验来模拟大规模微生物生产过程中可能发生的事故。使用细菌模型模拟了四种被认为最有可能对健康造成最大危害的事故类型。这些事故均与微生物发酵罐操作中出现的故障有关。在所有实验中均发生了表面的严重污染,但只有三种事故类型产生了可测量的气溶胶。