Stillman A E, Giordano G F
Am J Gastroenterol. 1983 Sep;78(9):589-92.
Two patients with extrahepatic biliary obstruction developed spur cell hemolytic anemia. Hemolysis and erythrocyte morphology reverted to normal when the obstruction was relieved. During the hemolytic phase, one patient's plasma converted normal erythrocytes to spur cells and normal plasma converted the patient's spur cells to normal morphology. The spur cells were discovered only when the patients' blood was examined under phase microscopy. We suggest that spur cells may occur in association with biliary obstruction more frequently than previously suspected and that their presence may be uncovered using phase microscopy.
两名肝外胆管梗阻患者发生了棘状细胞溶血性贫血。当梗阻解除时,溶血和红细胞形态恢复正常。在溶血期,一名患者的血浆可将正常红细胞转变为棘状细胞,而正常血浆可将该患者的棘状细胞转变为正常形态。仅在相差显微镜下检查患者血液时才发现棘状细胞。我们认为,棘状细胞可能比之前怀疑的更频繁地与胆管梗阻相关联,并且使用相差显微镜可能会发现它们的存在。