Mehta R, Oliver L D, Melillo D, Milliorn K, Flye W, Fish J
Am J Kidney Dis. 1983 Sep;3(2):124-8. doi: 10.1016/s0272-6386(83)80028-6.
This article describes a case of disseminated Mycobacterium chelonei infection in a renal transplant recipient. This patient, who underwent thoracic duct drainage prior to cadaveric renal transplantation, developed M chelonei bacteremia and numerous subcutaneous nodules a few weeks after transplantation. The M chelonei initially responded to amikacin and tetracycline. Because of side effects and bacterial resistance, however, these drugs had to be discontinued. Subsequent treatment with cefoxitin led to reduction in size of subcutaneous nodules, but control of the infection was not achieved until an intravascular nidus of infection at the anastomotic site of an arteriovenous fistula was removed.
本文描述了一例肾移植受者播散性龟分枝杆菌感染的病例。该患者在尸体肾移植前接受了胸导管引流,移植后几周出现龟分枝杆菌菌血症和大量皮下结节。龟分枝杆菌最初对阿米卡星和四环素治疗有反应。然而,由于副作用和细菌耐药性,这些药物不得不停用。随后使用头孢西丁治疗使皮下结节尺寸缩小,但直到动静脉瘘吻合部位的血管内感染病灶被清除,感染才得到控制。