人羊膜在体外特异性产生前列腺素E
Specific production of prostaglandin E by human amnion in vitro.
作者信息
Mitchell M D, Bibby J, Hicks B R, Turnbull A C
出版信息
Prostaglandins. 1978 Feb;15(2):377-82. doi: 10.1016/0090-6980(78)90177-6.
Prostaglandin production by intra-uterine human tissues has been investigated using a method of tissue superfusion. Tissues were obtained at elective Caesarean section and after spontaneous vaginal delivery. It was found that all the tissues studied (amnion, chorion, decidua and placenta) produced more prostaglandin E (PGE) and 13,14-dihydro-15-keto-prostaglandin F (PGFM - the major circulating metabolite of prostaglandin F) than prostaglandin F (PGF). Amnion produced significantly more PGE (but not PGF or PGFM) than any other tissue. Prostaglandin production by each tissue was similar whether it was taken at elective Caesarean section or after spontaneous vaginal delivery.
已使用组织灌流法对人子宫组织中前列腺素的产生进行了研究。组织取自择期剖宫产和自然阴道分娩后。结果发现，所有研究的组织（羊膜、绒毛膜、蜕膜和胎盘）产生的前列腺素E（PGE）和13,14-二氢-15-酮-前列腺素F（PGFM - 前列腺素F的主要循环代谢物）比前列腺素F（PGF）更多。羊膜产生的PGE（但不是PGF或PGFM）明显多于任何其他组织。无论组织取自择期剖宫产还是自然阴道分娩后，每个组织的前列腺素产生量相似。
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