Bjørneklett A
Scand J Gastroenterol Suppl. 1983;85:83-93.
Different aspects of the small bowel bacterial overgrowth syndrome are reviewed. Special emphasis is put on the newly recognized structural and functional abnormalities of the small intestinal mucosa, abnormalities that may not be fully reversed by effective antimicrobic therapy. The pathogenetic mechanisms involved in the malabsorption of different substances are discussed and the available diagnostic tests are briefly presented. The current therapy, surgical, medical and supportive, are outlined. It is pointed out that abnormal overgrowth flora of the small intestine can occur unassociated with malabsorption. Thus, the clinician must assess the potential benefit to be derived from treatment, once the presence of absorptive abnormalities is documented.
本文综述了小肠细菌过度生长综合征的不同方面。特别强调了小肠黏膜新发现的结构和功能异常，这些异常可能无法通过有效的抗菌治疗完全逆转。讨论了不同物质吸收不良所涉及的发病机制，并简要介绍了现有的诊断测试。概述了目前的治疗方法，包括手术、药物和支持治疗。指出小肠菌群异常过度生长可能与吸收不良无关。因此，一旦记录到吸收异常，临床医生必须评估治疗可能带来的潜在益处。
