Wright J P, Barbezat G O
S Afr Med J. 1983 Oct 8;64(16):626-7.
Fifty patients undergoing routine diagnostic jejunal biopsy with a Crosby capsule were entered into a double-blind study of intravenous domperidone 10 mg versus placebo given at the start of the procedure to see if transit time of the capsule could be reduced. In 3 patients from each group the capsule did not reach the jejunum. The mean time taken for the procedure (+/- SE) in the remaining patients was 25.1 +/- 4.4 minutes in the domperidone group and 27.3 +/- 3.8 minutes in the placebo group, showing that domperidone did not reduce the time taken for jejunal biopsy in this study. No side-effects were noted.
50名使用克罗斯比胶囊进行常规诊断性空肠活检的患者进入一项双盲研究，在操作开始时静脉注射10毫克多潘立酮与安慰剂，以观察胶囊的通过时间是否能够缩短。每组有3名患者的胶囊未到达空肠。其余患者中，多潘立酮组操作的平均时间（±标准误）为25.1±4.4分钟，安慰剂组为27.3±3.8分钟，表明在本研究中多潘立酮并未减少空肠活检所需时间。未观察到副作用。
