Drafta D, Franchi F, Luisi M, Stroe E
Endocrinologie. 1978 Jan-Mar;16(1):41-9.
The dynamics of urinary and plasma steroids (CPB and RIA) were simultaneously studied in a 36-yr-man with Cushing's syndrome due to adrenal carcinoma. The markedly increased basal excretion of 5-pregnenetriol, PG, PGT, DHA, THS and corticosteroids with nonsignificant changes during the endocrine tests decreased to normal levels after tumour removal. The basal low level of plasma testosterone, with nonsignificant changes during the endocrine tests, rose progressively after surgery. The steroid content of adrenal carcinoma tissue determined by CPB and RIA after LH-20-Sephadex CC separation revealed important proportion of unconjugated 17-OH-P.
对一名因肾上腺皮质癌导致库欣综合征的36岁男性，同时研究了尿液和血浆类固醇（CPB和RIA）的动态变化。5-孕烯三醇、PG、PGT、DHA、THS和皮质类固醇的基础排泄量显著增加，在内分泌试验期间变化不显著，肿瘤切除后降至正常水平。血浆睾酮基础水平较低，在内分泌试验期间变化不显著，术后逐渐升高。经LH-20-葡聚糖凝胶CC分离后，用CPB和RIA测定的肾上腺皮质癌组织类固醇含量显示，未结合的17-OH-P占重要比例。
