Taşcă C, Ionescu B, Secăreanu E
Endocrinologie. 1978 Jan-Mar;16(1):61-4.
The authors studied histopathologically, cytoenzymologically and morphometrically 64 cases of androgenic polycystic ovaries. The distinctive sign disclosed was a marked hyperplasia of theca interna. The mean values of this latter in the androgenic polycystic ovaries was of 87 mu +/- 19 as compared to that of 75 mu +/- 18 found for theca interna in the ovarian follicular cysts unaccompanied by endocrine symptoms. Large lipid-rich cells--the so-called androgenic cells--were often present in the polycystic ovary. Cytoenzymologically a high activity of glucose-6-phosphate dehydrogenase was assayed in theca interna and in the androgenic paralutein cells, while the lowest activity was shown by the 3beta-ol-hydroxysteroid dehydrogenase.
作者对64例雄激素性多囊卵巢进行了组织病理学、细胞酶学和形态计量学研究。所揭示的显著体征是卵泡膜内层明显增生。雄激素性多囊卵巢中卵泡膜内层的平均值为87μm±19，而无内分泌症状的卵巢滤泡囊肿中卵泡膜内层的平均值为75μm±18。多囊卵巢中常出现大量富含脂质的细胞，即所谓的雄激素细胞。细胞酶学检测显示，卵泡膜内层和雄激素性类黄体细胞中葡萄糖-6-磷酸脱氢酶活性较高，而3β-羟类固醇脱氢酶活性最低。
