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血小板计数、凝血因子及血清纤维蛋白/纤维蛋白原降解产物(FDP)在急性感染中的预后价值

Prognostic value of blood platelet counts, coagulation factors and serum fibrin/fibrinogen degradation products (FDP) in acute infections.

作者信息

Skånsberg P, Berg B

出版信息

Scand J Infect Dis. 1978;10(1):61-5. doi: 10.3109/inf.1978.10.issue-1.14.

DOI:10.3109/inf.1978.10.issue-1.14
PMID:635477
Abstract

Platelet counts, P&P, factor V and fibrin/fibrinogen degradation products (FDP) in serum were determined in 96 patients with 100 episodes of acute infections. The aim of the study was to evaluate the possible correlation between the tests, separately and in combination, and the outcome of the patients. The prognostic value was found to be dubious (0.05 greater than P greater than 0.01) as regards both a low platelet count and a decreased level of P&P and very low (P greater than 0.2) as regards factor V. On the other hand, the demonstration of a raised S-FDP as well as the presence of more than one pathological test was of distinct prognostic value (P less than 0.001). It is concluded that coagulation tests are useful as supportive aids in the prognostic evaluation of patients with acute infectious diseases.

摘要

对96例患者的100次急性感染发作进行了血清血小板计数、血浆鱼精蛋白副凝试验(3P试验)、因子V以及纤维蛋白/纤维蛋白原降解产物(FDP)的检测。本研究旨在评估各项检测单独及联合应用与患者预后之间的可能相关性。结果发现,低血小板计数和3P试验水平降低的预后价值存疑(0.05>P>0.01),因子V的预后价值极低(P>0.2)。另一方面,血清FDP升高以及存在不止一项病理检测具有明显的预后价值(P<0.001)。结论是,凝血检测作为辅助手段,对急性传染病患者的预后评估是有用的。

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