Varma R, Michos G A, Mesmer R E, Varma R S, Shirey R E
Neurosci Lett. 1983 Aug 19;39(1):105-11. doi: 10.1016/0304-3940(83)90173-8.
As compared to controls and epileptics with controlled seizures, serum beta-glucuronidase enzyme is elevated significantly in epileptics with uncontrolled seizures. The enzyme begins to rise just before the seizure, remains elevated during, and for some time after the seizure and then begins to decline, unless another seizure follows the first seizure. The enzyme is not elevated in controlled diabetes patients without any secondary complications. But the enzyme is also elevated in other pathological conditions which involve increased connective tissue catabolism. However, the enzyme is elevated constantly and all the time in these conditions, in contrast with its elevation in uncontrolled epilepsy only close to the seizures.
与对照组和癫痫发作得到控制的癫痫患者相比，癫痫发作未得到控制的患者血清β-葡萄糖醛酸酶显著升高。该酶在癫痫发作前开始升高，在发作期间及发作后的一段时间内保持升高，然后开始下降，除非在首次发作后又出现另一次发作。在没有任何继发性并发症的糖尿病控制患者中，该酶不会升高。但在其他涉及结缔组织分解代谢增加的病理状况中，该酶也会升高。然而，在这些情况下，该酶持续不断地升高，这与它仅在癫痫发作未得到控制时靠近发作时升高形成对比。
