Drettner B, Svensson C
Rhinology. 1983 Sep;21(3):251-5.
Seventeen patients treated for recurrent epistaxis due to Osler's disease in the nose were followed up 6 months - 19 years after treatment. A written questionnaire was answered by 13 of the 14 patients surviving at follow-up. They had undergone either septal dermoplasty, or irradiation with 1200--1400 rad on both sides of the nose, or both kinds of treatment. All patients were satisfied with their treatment. The amount of nose-bleeding was reduced in all but one of the surgically treated patients, and the frequency was reduced in nine of the 13 patients. Nasal crusts, often causing nasal obstruction, were a problem, at least shortly after operation. Pathological vessels were found within the skin graft at secondary operation in one patient, showing that telangiectasia can develop in the graft area and cause recurrences of the epistaxis, sometimes necessitating further operations.
对17例因鼻部奥斯勒病导致反复鼻出血而接受治疗的患者进行了治疗后6个月至19年的随访。随访时存活的14例患者中有13例回答了书面问卷。他们要么接受了鼻中隔真皮成形术，要么双侧鼻子接受了1200 - 1400拉德的照射，要么接受了两种治疗。所有患者对其治疗都很满意。除1例手术治疗的患者外，所有患者鼻出血的量都有所减少，13例患者中有9例鼻出血频率降低。鼻痂常导致鼻塞，至少在术后短期内是个问题。1例患者在二次手术时在皮肤移植物内发现了病理性血管，表明移植区域可发生毛细血管扩张并导致鼻出血复发，有时需要进一步手术。
