Toledo-Pereyra L H, Zeichner W D, Baskin S, McNichol L, Lin W, Thavarajah K, Whitten J
Am Surg. 1983 Nov;49(11):632-6.
One hundred consecutive kidney transplants in 89 patients performed at a single center were analyzed to assess the relationship between patient survival and various high-risk factors present prior to transplantation. Each individual risk factor was given a relative weight which contributed to a cumulative risk index for each patient. Based on these risk indices, patients were placed in four risk categories: 1) good risk, 2) high risk, 3) very high risk, and 4) extremely high risk. Analysis of the survival data for each of these groups indicated that as the risk increased, survival decreased. Actuarial patient survival for the good risk group (n = 37) and high risk group (n = 27) were 97.2 per cent and 88.5 per cent, respectively. The very high risk group (n = 15) and extremely high risk group (n = 21) had decreased survival of 45.8 per cent and 38.2 per cent, respectively. Therefore, although our system of high-risk classification is not fully evolved, its application even in the present form could be of considerable aid in transplantation decision making.
对某单一中心89例患者进行的100例连续肾移植进行分析，以评估患者生存率与移植前存在的各种高危因素之间的关系。每个个体危险因素都被赋予一个相对权重，该权重构成了每个患者的累积风险指数。基于这些风险指数，患者被分为四个风险类别：1）低风险，2）高风险，3）非常高风险，4）极高风险。对这些组中每组的生存数据进行分析表明，随着风险增加，生存率降低。低风险组（n = 37）和高风险组（n = 27）的患者精算生存率分别为97.2%和88.5%。非常高风险组（n = 15）和极高风险组（n = 21）的生存率分别降至45.8%和38.2%。因此，尽管我们的高危分类系统尚未完全完善，但即使以目前的形式应用，它也可能对移植决策有很大帮助。
