Goodwin D W
Hosp Community Psychiatry. 1983 Nov;34(11):1031-4. doi: 10.1176/ps.34.11.1031.
One method of investigating the genetic etiology of alcoholism is to study individuals who were separated soon after birth from their alcoholic biological parents. The author and his colleagues conducted a series of such studies in Denmark; they concluded that, despite little exposure to the alcoholic biological parent, the sons of alcoholics were about four times more likely to be alcoholic than were the sons of nonalcoholics. They also found that having an alcoholic biological parent did not increase the sons' risk of developing psychiatric disorders other than alcoholism. After reviewing the results of four other studies that resemble the Danish series, the author discusses two investigations of the possible mode of transmission of alcoholism and describes further evidence for the proposed diagnostic category of familial alcoholism.
研究酗酒遗传病因的一种方法是研究那些在出生后不久就与其酗酒的亲生父母分离的个体。作者及其同事在丹麦进行了一系列此类研究；他们得出结论，尽管与酗酒的亲生父母接触很少，但酗酒者的儿子成为酗酒者的可能性是非酗酒者儿子的四倍左右。他们还发现，有一个酗酒的亲生父母并不会增加儿子患除酗酒以外的精神疾病的风险。在回顾了其他四项与丹麦系列研究相似的研究结果后，作者讨论了两项关于酗酒可能传播方式的调查，并描述了支持所提议的家族性酗酒诊断类别的进一步证据。
