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一项以富含¹³C的淀粉作为示踪剂对人体“淀粉阻断剂”进行的研究。

A study of 'starch blockers' in man using 13C-enriched starch as a tracer.

作者信息

Garrow J S, Scott P F, Heels S, Nair K S, Halliday D

出版信息

Hum Nutr Clin Nutr. 1983 Jul;37(4):301-5.

PMID:6358146
Abstract

It is claimed that commercial preparations of an alpha-amylase inhibitor, taken in tablet form 10 min before a meal, will inhibit the digestion of up to 100 g starch in the following meal. This was tested by giving five obese women three meals each containing cornflour enriched with 13C after a tablet of 'Starchex' or 'Calorex' or a placebo, in randomized sequence. The response to the meal in the rate of evolution of 13CO2, the increase in plasma insulin and the increase in blood sugar did not differ with the type of tablet which preceded the meal. We conclude that these starch-blocker tablets do not affect starch digestion or absorption in vivo.

摘要

据称,一种α-淀粉酶抑制剂的商业制剂,在饭前10分钟以片剂形式服用,将抑制下一顿饭中多达100克淀粉的消化。通过让五名肥胖女性在服用一片“Starchex”或“Calorex”或安慰剂后,以随机顺序分别食用三餐,每餐都含有富含13C的玉米淀粉,对这一说法进行了测试。饭前服用的片剂类型不同,对餐食在13CO2释放速率、血浆胰岛素增加和血糖增加方面的反应并无差异。我们得出结论,这些淀粉阻滞剂片剂在体内不影响淀粉的消化或吸收。

相似文献

1
A study of 'starch blockers' in man using 13C-enriched starch as a tracer.一项以富含¹³C的淀粉作为示踪剂对人体“淀粉阻断剂”进行的研究。
Hum Nutr Clin Nutr. 1983 Jul;37(4):301-5.
2
Starch blockers--their effect on calorie absorption from a high-starch meal.淀粉阻滞剂——它们对高淀粉餐中热量吸收的影响。
N Engl J Med. 1982 Dec 2;307(23):1413-6. doi: 10.1056/NEJM198212023072301.
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Partially purified white bean amylase inhibitor reduces starch digestion in vitro and inactivates intraduodenal amylase in humans.部分纯化的白豆淀粉酶抑制剂在体外可减少淀粉消化,并使人体十二指肠内的淀粉酶失活。
Gastroenterology. 1985 Jun;88(6):1895-902. doi: 10.1016/0016-5085(85)90016-2.
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Intestinal transport and fermentation of resistant starch evaluated by the hydrogen breath test.通过氢呼气试验评估抗性淀粉的肠道转运和发酵。
Eur J Clin Nutr. 1994 Oct;48(10):692-701.
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Inhibition of starch absorption by tendamistate (an alpha-amylase inactivator).
S Afr Med J. 1983 Aug 20;64(8):284-5.
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Starch blockers.淀粉阻滞剂
Clin Pharm. 1982 Nov-Dec;1(6):493.
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Starch digestion in young children with cystic fibrosis measured using a 13C breath test.采用¹³C呼气试验测定囊性纤维化幼儿的淀粉消化情况。
Pediatr Res. 1992 Jul;32(1):45-9. doi: 10.1203/00006450-199207000-00009.
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Effects of a commercial starch blocker preparation on carbohydrate digestion and absorption: in vivo and in vitro studies.
Am J Clin Nutr. 1983 Oct;38(4):498-503. doi: 10.1093/ajcn/38.4.498.
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Starch blockers do not block starch digestion.淀粉阻滞剂并不能阻止淀粉的消化。
Nutr Rev. 1985 Feb;43(2):46-8. doi: 10.1111/j.1753-4887.1985.tb06854.x.
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Low-dose acarbose does not delay digestion of starch but reduces its bioavailability.低剂量阿卡波糖不会延迟淀粉的消化,但会降低其生物利用度。
Diabet Med. 2007 Jun;24(6):600-6. doi: 10.1111/j.1464-5491.2007.02115.x. Epub 2007 Mar 22.

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