Price L A, Hill B T
S Afr Med J. 1983 Dec 10;64(25):987-94.
A clinically proven experimentally based method of administering intensive combination chemotherapy, which is much safer than methods used in the past, has been developed over the past 13 years. Clinical studies of several different tumour types over several thousand treatment cycles have confirmed the validity of this approach. The implications of this new method of administering chemotherapy to patients with advanced disease are discussed and its potential for improving the 'cure' rates for certain common 'solid' tumours such as breast, small-cell lung, bladder, prostate and ovarian carcinomas and squamous cell carcinomas of the head and neck is outlined.
在过去13年里，已经开发出一种基于实验且经临床验证的强化联合化疗给药方法，该方法比过去使用的方法安全得多。对几种不同肿瘤类型进行的数千个治疗周期的临床研究证实了这种方法的有效性。本文讨论了这种新的化疗给药方法对晚期疾病患者的影响，并概述了其提高某些常见“实体”肿瘤（如乳腺癌、小细胞肺癌、膀胱癌、前列腺癌和卵巢癌以及头颈部鳞状细胞癌）“治愈”率的潜力。
