Ganzer U, Bier H, Bachert C
Laryngol Rhinol Otol (Stuttg). 1987 Apr;66(4):200-4.
Chemotherapy of head and neck carcinomas has been the subject of 111 relevant publications reporting on more than 4,500 patients in the international literature of the past five years. Results of similar treatment protocols have been grouped together and tumour remission and survival time determined. Chemotherapy did not result in cure or increased survival times, neither alone nor in combination with irradiation nor when applied as adjuvant treatment. Inductive chemotherapy may result in producing a favourable effect on the prognosis of advanced carcinomas. The beneficial character of palliative chemotherapy is a generally accepted fact. Improvement of treatment results will be achieved only via centrally coordinated, randomised and prospective studies as well as by intensive fundamental research.
头颈部癌的化疗一直是过去五年国际文献中111篇相关出版物的主题，这些出版物报道了4500多名患者。已将类似治疗方案的结果进行汇总，并确定了肿瘤缓解情况和生存时间。化疗无论是单独使用、与放疗联合使用还是作为辅助治疗，均未导致治愈或延长生存时间。诱导化疗可能会对晚期癌症的预后产生有利影响。姑息化疗的有益特性是一个普遍公认的事实。只有通过集中协调、随机和前瞻性研究以及深入的基础研究，才能实现治疗效果的改善。
