甲氧苄啶-磺胺甲恶唑对霍乱（埃尔托型）弧菌清除的影响：一项对比研究。
Effect of trimethoprim-sulphamethoxazole on vibrio clearance in cholera (El Tor): a comparative study.
作者信息
Dutta J K, Santhanam S, Misra B S, Ray S N
出版信息
Trans R Soc Trop Med Hyg. 1978;72(1):40-2. doi: 10.1016/0035-9203(78)90297-3.
PMID:635974
Abstract
The efficacy of trimethoprim-sulphamethoxazole (TMP-SMX) has been compared with that of tetracycline and chloramphenicol in 175 bacteriologically confirmed cases of cholera admitted to the Infectious Diseases Hospital Delhi. Vibrio cholerae, biotype El Tor, serotype ogawa, were isolated from all the patients. TMP-SMX showed greater in vitro inhibition and earlier eradication from the intestinal tract and is recommended as a suitable vibriocidal agent against cholera.
摘要
在德里传染病医院收治的175例经细菌学确诊的霍乱病例中，对甲氧苄啶-磺胺甲恶唑（TMP-SMX）与四环素和氯霉素的疗效进行了比较。所有患者均分离出霍乱弧菌，埃尔托生物型，小川血清型。TMP-SMX在体外显示出更强的抑制作用，能更早地从肠道清除，因此被推荐作为一种合适的抗霍乱杀弧菌剂。
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