Corless J K, Middleton H M
Arch Intern Med. 1983 Dec;143(12):2291-4. doi: 10.1001/archinte.143.12.2291.
The physiology of the liver involves metabolism, excretion, and body defense. Within the context of metabolism, the liver is the site of a multitude of biochemical reactions essential to the human organism; included are synthesis, degradation, interconversion, storage, and biotransformation. A working knowledge of the relationship between structure and function and of hepatic processes under normal conditions is essential for understanding the derangements observed in clinical diseases affecting the liver. Our overview of hepatic physiology highlights some of these facets of normal hepatic anatomy and function of special relevance to the physician confronting liver dysfunction and its varied clinical consequences.
肝脏的生理功能涉及代谢、排泄和身体防御。在代谢方面,肝脏是人体不可或缺的众多生化反应发生的场所;这些反应包括合成、降解、相互转化、储存和生物转化。了解正常情况下肝脏的结构与功能之间的关系以及肝脏的生理过程,对于理解影响肝脏的临床疾病中出现的功能紊乱至关重要。我们对肝脏生理学的概述着重介绍了正常肝脏解剖结构和功能的一些方面,这些方面对于面对肝功能障碍及其各种临床后果的医生尤为重要。