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[耐辐射微球菌的抗辐射机制]

[Radioresistance mechanisms of Micrococcus radiodurans].

作者信息

Samoĭlenko I I

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1983(10):4-17.

PMID:6360221
Abstract

The modern conceptions on the molecular mechanisms of Micrococcus radiodurans viability under the action of ionized radiation have been considered. Factors providing a high level of the bacterium radioresistance-the peculiarities of the cell wall structure, membranes, DNA, the redundancy of genetic information, the multiplicity of sites of DNA attachment to the membrane, a high level of antioxidant and antiradical systems-have been analysed. It has been shown that the efficiency of accurate, error-free, well balanced DNA repair system in connection with M. radiodurans properties mentioned provides a high radiation resistance of this microorganism.

摘要

本文探讨了现代关于耐辐射微球菌在电离辐射作用下存活的分子机制的概念。分析了赋予该细菌高水平辐射抗性的因素,包括细胞壁结构、细胞膜、DNA的特性、遗传信息的冗余性、DNA与膜附着位点的多样性、高水平的抗氧化和抗自由基系统。结果表明,结合上述耐辐射微球菌的特性,精确、无差错且平衡良好的DNA修复系统的效率赋予了该微生物高辐射抗性。

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