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[耐辐射微球菌细胞中致密染色体辐射后修复过程的遗传控制]

[Genetic control of the processes of postradiation repair of a compact chromosome in Micrococcus radiodurans cells].

作者信息

Kudriashova N Iu, Groshev V V, Shestakov S V

出版信息

Radiobiologiia. 1984 Sep-Oct;24(5):603-6.

PMID:6505148
Abstract

X-irradiation of Micrococcus radiodurans cells with sublethal doses caused disturbances in the structure of a membrane-bound compact chromosome. Recovery of the compact chromosome occurred during the postirradiation incubation of the wild type cells and cells of the UVS-17 mutant deficient in DNA-polymerase. This process was blocked in cells of rec-30 mutant with the impaired system of genetic recombination: this is indicative of an important role played by rec-30 gene product in the postirradiation recovery of the compact chromosome in M. radiodurans cells.

摘要

用亚致死剂量的X射线照射耐辐射微球菌细胞,会导致膜结合紧密染色体的结构紊乱。在野生型细胞和缺乏DNA聚合酶的UVS - 17突变体细胞的辐照后培养过程中,紧密染色体得以恢复。在遗传重组系统受损的rec - 30突变体细胞中,这一过程受到阻碍:这表明rec - 30基因产物在耐辐射微球菌细胞紧密染色体的辐照后恢复中发挥着重要作用。

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