Worthen G S, Henson P M
Clin Lab Med. 1983 Dec;3(4):601-17.
The role of the complement system in generating an acute inflammatory response in the lung, manifested particularly by the presence of neutrophils, and the role of these neutrophils in altering lung microvascular permeability are examined. Although it is not possible at this time to reconcile all the experimental data so as to provide a unifying hypothesis of the pathogenesis of acute lung injury, the mechanisms discussed in this article provide clues not only about lung injury itself, but also about the basic mechanisms of inflammation.
研究了补体系统在引发肺部急性炎症反应（尤其以中性粒细胞的存在为特征）中的作用，以及这些中性粒细胞在改变肺微血管通透性方面的作用。尽管目前尚无法整合所有实验数据以提供急性肺损伤发病机制的统一假说，但本文讨论的机制不仅为肺损伤本身，也为炎症的基本机制提供了线索。
