Mohnike W, Weber H C, Schmidt J, Rasch J, Bach H, Heine H, Faulhaber H D
Eur J Nucl Med. 1983;8(11):471-6. doi: 10.1007/BF00598903.
A new non-invasive method for investigating total coronary blood supply is presented. This method is based on the principle of indicator dilution of a radio-nuclide bolus (99Tc), requiring a scintillation camera with high sensitivity and high picture resolution. The first findings obtained from 83 patients are shown. With 4.61 +/- 1.19% of cardiac output the mean values of the rates of coronary perfusion obtained at rest in subjects with a normal heart differed significantly from those obtained for patients with certain coronary occlusions (8.18 +/- 3.99% of cardiac output) and from those obtained for hypertensive patients (Stages I-III). Double examinations carried out on 20 patients yielded an adequate reproducibility. The mean deviation of the double examinations from one another was 16%.
本文介绍了一种用于研究冠状动脉总供血量的新型非侵入性方法。该方法基于放射性核素团注（99Tc）指示剂稀释原理，需要一台具有高灵敏度和高图像分辨率的闪烁相机。展示了从83例患者获得的初步研究结果。心脏正常的受试者静息时获得的冠状动脉灌注率平均值为心输出量的4.61±1.19%，这与某些冠状动脉闭塞患者（心输出量的8.18±3.99%）以及高血压患者（I - III期）获得的结果有显著差异。对20例患者进行的重复检查具有足够的可重复性。重复检查之间的平均偏差为16%。
