Flamm J, Sagaster P, Micksche M
Urologe A. 1978 Mar;17(2):109-10.
Forty patients with urinary bladder tumors (26 cancer and 14 papilloma) were investigated by clinical and immunological methods. Patients with Stage I and II bladder cancer had a decrease in their delayed cutaneous hypersensitivity reactions in comparison to healthy controls. The same was found in patients with proliferating papillomas (WHO I) and benign papillomas. Patients with carcinoma in Stages III and IV had a reduced reactivity to recall antigens and could be immunized to a significantly lesser degree with primary antigens. In most cases a transurethral resection of the tumor was followed by radiotherapy. In four patients local immunotherapy was performed after resection of most of the tumor mass.
采用临床和免疫学方法对40例膀胱肿瘤患者（26例癌症和14例乳头状瘤）进行了研究。与健康对照组相比，I期和II期膀胱癌患者的迟发型皮肤超敏反应有所降低。增殖性乳头状瘤（WHO I级）和良性乳头状瘤患者也有同样的情况。III期和IV期癌症患者对回忆抗原的反应性降低，用初级抗原进行免疫的程度明显较低。在大多数情况下，肿瘤经尿道切除术后进行放射治疗。4例患者在大部分肿瘤肿块切除后进行了局部免疫治疗。
