Lenzin A, Cavalli F, Sonntag R, Zimmermann A
Urologe A. 1978 Mar;17(2):105-8.
A report is presented of a female patient who developed an extensive bladder carcinoma with severe hemorrhaging after many years of treatment with cyclophosphamide for multiple myeloma. The severe hemorrhage could only be controlled by drainage of the urine. The possible causes of the development of a second neoplasia, particularly of urinary bladder carcinoma following long-term therapy with cyclophosphamide, are discussed.
报告了一名女性患者，她在接受环磷酰胺治疗多发性骨髓瘤多年后，患上了广泛的膀胱癌并伴有严重出血。严重出血只能通过尿液引流来控制。讨论了长期使用环磷酰胺治疗后发生第二种肿瘤，特别是膀胱癌的可能原因。
