Aldrich M S, Burke J M, Gulati S M
Stroke. 1983 Nov-Dec;14(6):1001-4. doi: 10.1161/01.str.14.6.1001.
A young man with a history of two strokes was found to have serologic evidence of a prior syphilitic infection, abnormal spinal fluid, and angiographic evidence of diffuse intracranial and extracranial angiopathy which we believe was due to tertiary syphilis, although his use of oral amphetamines cannot be ruled out as a contributing factor. This is the first reported case in which angiography has demonstrated both intracranial and extracranial disease arterial disease due to neurosyphilis. Since syphilis can produce diffuse cerebral arterial changes, this diagnosis should be considered in young patients with stroke even when non-treponemal serologic tests are negative.
一名有两次中风病史的年轻男子被发现有既往梅毒感染的血清学证据、脑脊液异常以及弥漫性颅内和颅外血管病的血管造影证据，我们认为这是由三期梅毒引起的，尽管不能排除他使用口服苯丙胺作为一个促成因素。这是第一例报告的血管造影显示因神经梅毒导致颅内和颅外动脉疾病的病例。由于梅毒可引起弥漫性脑动脉改变，即使非梅毒螺旋体血清学检测为阴性，对于中风的年轻患者也应考虑这一诊断。
