Lizana J, Moberg P J, Eneroth P
Arch Androl. 1983 Dec;11(3):225-32. doi: 10.3109/01485018308987486.
Analyses of split ejaculates and urine voided before and after prostatic massage have been used to evaluate the origin of beta2-microglobulin (b2m) and carcinoembryonic antigen (CEA) in human semen. CEA and b2m were present in rather high concentrations in all the fractions of the split ejaculates. The urine voided after massage of the prostate also contained increased levels of CEA and beta2-microglobulin. Split ejaculates, selected from the electrophoretic pattern obtained for each fraction, revealed that b2m in seminal plasma originates from the prostate and seminal vesicles in equal amounts. Besides the "free" b2m in seminal plasma, human semen contains a sperm-bound b2m fraction. Carcinoembryonic antigen was found in the highest concentrations in the second fraction of split ejaculates indicating that it originates mainly from the prostate.
对分段射精以及前列腺按摩前后排出的尿液进行分析，已用于评估人精液中β2-微球蛋白（b2m）和癌胚抗原（CEA）的来源。在分段射精的所有部分中，CEA和b2m的浓度都相当高。前列腺按摩后排尿中的CEA和β2-微球蛋白水平也有所升高。从每个部分获得的电泳图谱中选择的分段射精显示，精浆中的b2m等量地来源于前列腺和精囊。除了精浆中的“游离”b2m外，人精液还含有与精子结合的b2m部分。在分段射精的第二部分中发现癌胚抗原的浓度最高，表明它主要来源于前列腺。
