Pirogov A I, Trakhtenberg A Kh, Kadirov A M, Agamova K A, Krylova G P
Vopr Onkol. 1978;24(2):11-7.
The peculiarities of clinical manifestations of glandular carcinoma of the lung have been studied, an account is taken of histological tumor variants and the degree of tumor proliferation. The results of treatment are analysed in relation to the prognosis of the disease in 305 patients. The peculiar clinical course of lung adenocarcinoma seems to be due to the predominantly peripheral kind of the tumor and relatively prompt lympho-hematogenic metastasization. Marked anaplasia of the tumor revealed morphologically is usually indicative of the dissemination even in insignificant local spread. Satisfactory results of surgical treatment are gained only in early stages (I--II), mainly in patients with high-differentiated adenocarcinoma.