Grigorian L S, Petrova A S
Vopr Onkol. 1978;24(2):53-8.
Cytologic assay of metastatic involvement of lymph nodes may be used along with histological studies as a reliable adjunct for morphological diagnosis, that makes possible in many cases to determine not only the epithelial origin of the affection but also to characterize its histological pattern. However, the cytologic diagnosis of undifferentiated cancer metastases is frequently rather difficult in relation to establishing the differential diagnosis between the former and other affections of lymph nodes. A careful, and sometimes repeated analysis of the material, taking into account the clinical data and cytochemical findings, contributes to greater efficiency of a cytologic method. The perspective use of cytochemical reactions as additional criteria for the diagnosis of undifferentiated cancer necessitates their further elaboration and study.
淋巴结转移累及的细胞学检测可与组织学研究一起作为形态学诊断的可靠辅助手段，这在许多情况下不仅能够确定病变的上皮起源，还能对其组织学模式进行特征描述。然而，未分化癌转移的细胞学诊断在区分前者与淋巴结的其他病变时往往相当困难。仔细且有时需反复分析材料，并考虑临床数据和细胞化学结果，有助于提高细胞学方法的效率。将细胞化学反应作为诊断未分化癌的额外标准的前瞻性应用需要对其进行进一步的完善和研究。
