Landau I T, Madden J E
Physiol Behav. 1983 Nov;31(5):679-85. doi: 10.1016/s0031-9384(83)80003-1.
Two experiments were conducted that assessed the effect of varying levels of female proceptive/attractive behaviors on male sexual preferences in sexually experienced rats. In Experiment 1, adult ovariectomized Sprague-Dawley rats were brought into behavioral estrus by a combination of estradiol-17 beta-benzoate (EB) (4 micrograms) and progesterone (500 micrograms). In addition, females received an injection of either the anti-estrogen CI-628 (1 mg) or the control vehicle (10% ethanol) only. In tests for sexual responsiveness, CI-628 caused a 3 to 4 fold decline in proceptive behavior along with a small but significant decline in receptivity. When individual males were placed in a testing arena with a pair of receptive females, only one of which received CI-628, males displayed a preference for the control-group females, as measured by overall copulatory rate. However, males did not display a consistent preference towards females of either treatment, as measured by choice of female for ejaculation. Similarly, there were no significant correlations between female proceptive behaviors and either overall copulatory rate or ejaculation. In Experiment 2, females came into behavioral estrus after being given four daily injections of EB followed by either a single injection of progesterone or just the oil vehicle. The absence of progesterone caused a significant decline in receptivity and almost entirely eliminated proceptive behaviors. When males were tested with a pair of females, only one of which received progesterone, males preferred the progesterone-injected female as measured by overall copulatory rate. However, similar to Experiment 1, no consistent preferences were evident when measured by using choice of female for ejaculation.(ABSTRACT TRUNCATED AT 250 WORDS)
进行了两项实验，评估了不同程度的雌性求偶/吸引行为对有性经验大鼠雄性性偏好的影响。在实验1中，成年去卵巢的斯普拉格-道利大鼠通过结合使用雌二醇-17β-苯甲酸酯（EB）（4微克）和孕酮（500微克）进入行为发情期。此外，雌性大鼠仅接受抗雌激素CI-628（1毫克）或对照载体（10%乙醇）的注射。在性反应测试中，CI-628导致求偶行为下降3至4倍，同时接受性也有小幅但显著的下降。当将个体雄性置于测试场地中与一对接受测试的雌性大鼠在一起时，其中只有一只接受CI-628，通过总体交配率衡量，雄性表现出对对照组雌性的偏好。然而，通过射精时对雌性的选择衡量，雄性对两种处理的雌性均未表现出一致的偏好。同样，雌性求偶行为与总体交配率或射精之间均无显著相关性。在实验2中，雌性大鼠在每天注射四次EB，随后单次注射孕酮或仅注射油载体后进入行为发情期。孕酮的缺失导致接受性显著下降，并几乎完全消除了求偶行为。当用一对雌性大鼠对雄性进行测试时，其中只有一只接受孕酮，通过总体交配率衡量，雄性更喜欢注射孕酮的雌性。然而，与实验1类似，通过射精时对雌性的选择衡量时，没有明显的一致偏好。（摘要截短于250字）
