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[致敏大生物体实验性角结膜炎中外周血中性粒细胞的吞噬活性]

[Neutrophil phagocytic activity of the peripheral blood in experimental keratoconjunctivitis in a sensitized macroorganism].

作者信息

Milovidova O V, Matveeva E A, Ozherel'eva N G

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1983 Dec(12):60-4.

PMID:6364656
Abstract

The study of the characteristics of the phagocytic activity of peripheral blood neutrophils (the activity and intensity of phagocytosis, the index of its completeness) in the sensitized organism in experimental keratoconjunctivitis caused by Staphylococcus aureus and Escherichia coli has revealed a decrease in the phagocytic function of neutrophils. Still more pronounced suppression of the ingestive and digestive activity of leukocytes has been observed in cases of the combined action of bacterial allergens and benzylpenicillin potassium, which probably accounts for the ineffectiveness of the penicillin treatment of bacterial keratoconjunctivitis.

摘要

对金黄色葡萄球菌和大肠杆菌引起的实验性角结膜炎致敏机体中,外周血中性粒细胞吞噬活性特征(吞噬作用的活性和强度、其完整性指标)的研究表明,中性粒细胞的吞噬功能有所下降。在细菌过敏原和苄青霉素钾联合作用的情况下,观察到白细胞摄取和消化活性受到更明显的抑制,这可能是青霉素治疗细菌性角结膜炎无效的原因。

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