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[荧光密螺旋体抗体吸收试验在先天性梅毒诊断中的应用]

[The FTA-abs test in the diagnosis of congenital syphilis].

作者信息

Lorente Ortuño S, Fraile Fariñas M T, Torregrosa Sánchez R, Alabajos Ibáñez M D, Sanchís-Bayarri Vaillant V

出版信息

An Esp Pediatr. 1983 Dec;19(6):481-7.

PMID:6364907
Abstract

Present survey has analysed the results obtained from 13 children whose FTA-abs (IgG) test proved to be positive. For assessing their anti-Treponemal and reaginic antibodies, the RPR, passive hemagglutination (MHA-TP) and FTA-abs trials were carried out, the existence of specific IgG and IgM being noticed from the latter. Out of the 13 samples subject to our analyses, 7 showed some specific IgM antibodies, with the existence of a congenital syphilis being clinically assessed from three of them, whereas the remaining 6 samples only showed some IgG antibodies. The need for an early diagnosis during the first and third quarters of pregnancy is indicated, through a reaginic (RPR o VDRL) trial or a treponemic (MHA-TP) one, as well as the assessing of anti-Treponema pallidum antibodies in the umbilical cord blood, where a positive luetic serology appears to be the case during the period of pregnancy.

摘要

本次调查分析了13名FTA-abs(IgG)检测呈阳性儿童的检测结果。为评估他们的抗梅毒螺旋体抗体和反应素抗体,进行了快速血浆反应素环状卡片试验(RPR)、被动血凝试验(MHA-TP)和荧光螺旋体抗体吸收试验(FTA-abs),从后者中检测到特异性IgG和IgM的存在。在我们分析的13个样本中,7个显示出一些特异性IgM抗体,其中3个经临床评估存在先天性梅毒,而其余6个样本仅显示出一些IgG抗体。这表明在妊娠的第一和第三季度需要通过反应素试验(RPR或VDRL)或梅毒螺旋体试验(MHA-TP)以及评估脐带血中的抗梅毒螺旋体抗体进行早期诊断,在孕期若梅毒血清学检测呈阳性则属于这种情况。

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