Tashiro Y
Cell Struct Funct. 1983 Jun;8(2):91-107. doi: 10.1247/csf.8.91.
A cell is surrounded by a plasma membrane. It contains various organelles, most of which are enclosed by limiting membranes. The intracellular space is thus divided into a number of subcellular compartments. Structurally, a cell is composed of membranes and the spaces enclosed by those membranes. In order to classify these compartments, the extracellular space has been designated S1 and whenever a unit membrane structure is crossed to arrive at the next space, one is added to term; the cytoplasmic space becomes S2, the intraluminal space of the endoplasmic reticulum and the intermembrane space of the mitochondria S3, and the matrix space of the mitochondria S4. Similarly, the plasma membrane is M1, the outer membrane of the mitochondria M2, and the inner counterpart M3. This classification of the subcellular compartments is useful in understanding a number of complicated cellular structures and functions. The intracellular transport of newly synthesized protein (protein topogenesis) and the probable development of subcellular organelles during phylogenesis of eukaryotic cells is discussed in terms of these subcellular compartments.
细胞被质膜包围。它包含各种细胞器，其中大多数被界膜所包围。因此，细胞内空间被划分为多个亚细胞区室。从结构上讲，细胞由膜以及这些膜所包围的空间组成。为了对这些区室进行分类，细胞外空间被指定为S1，每当穿过一个单位膜结构到达下一个空间时，就在术语上加1；细胞质空间变为S2，内质网的管腔空间和线粒体的膜间隙为S3，线粒体的基质空间为S4。同样，质膜为M1，线粒体的外膜为M2，内膜为M3。这种亚细胞区室的分类有助于理解许多复杂的细胞结构和功能。本文根据这些亚细胞区室讨论了真核细胞系统发育过程中新合成蛋白质的细胞内运输（蛋白质拓扑发生）以及亚细胞器可能的发育情况。
