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动脉血压与血浆血管加压素:家兔延髓尾端腹外侧神经元的调节作用

Arterial pressure and plasma vasopressin: regulation by neurons in the caudal ventrolateral medulla of the rabbit.

作者信息

Blessing W W, Sved A F, Reis D J

出版信息

Clin Exp Hypertens A. 1984;6(1-2):149-56. doi: 10.3109/10641968409062557.

Abstract

Experiments in the anesthetized rabbit have demonstrated that the caudal ventrolateral medulla oblongata contains tonically active vasodepressor neurons which are themselves inhibited by GABAergic and glycine-like inputs. Alteration of neuronal function in this region also elevates plasma vasopressin levels, contributing to, but not completely accounting for, the hypertension and pulmonary edema observed after destruction of neurons in the region.

摘要

对麻醉兔的实验表明,延髓尾端腹外侧区含有持续活跃的血管减压神经元,这些神经元本身受到γ-氨基丁酸能和甘氨酸样输入的抑制。该区域神经元功能的改变也会升高血浆血管加压素水平,这有助于但不能完全解释该区域神经元破坏后出现的高血压和肺水肿。

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