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脑干中心血管细胞群的鉴定。

Identification of cardiovascular cell groups in the brain stem.

作者信息

Dampney R A, Goodchild A K, Tan E

出版信息

Clin Exp Hypertens A. 1984;6(1-2):205-20. doi: 10.3109/10641968409062561.

DOI:10.3109/10641968409062561
PMID:6365367
Abstract

There is now good evidence that there are several distinct groups of cells in the brain stem that are capable of inducing marked changes in cardiovascular function. This paper briefly reviews the results of recent experiments which have identified cardiovascular cell groups in the rostral ventrolateral and dorsomedial medulla, and in the periaqueductal grey and ventral tegmentum of the midbrain. Results of our experiments as well as those of others suggest that excitation of cardiovascular cell groups in the lower brain stem leads to an undifferentiated generalized increase or decrease in sympathetic activity, whereas excitation of certain midbrain cell groups can evoke a highly co-ordinated pattern of autonomic and respiratory changes that closely resembles the pattern associated with certain behaviours in the conscious animal.

摘要

现在有充分的证据表明,脑干中有几组不同的细胞能够引起心血管功能的显著变化。本文简要回顾了最近的实验结果,这些实验确定了延髓头端腹外侧和背内侧以及中脑导水管周围灰质和腹侧被盖区的心血管细胞群。我们以及其他人的实验结果表明,脑干下部心血管细胞群的兴奋会导致交感神经活动出现无差异的普遍增加或减少,而某些中脑细胞群的兴奋则能引发自主神经和呼吸变化的高度协调模式,这与有意识动物的某些行为相关模式非常相似。

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1
Identification of cardiovascular cell groups in the brain stem.脑干中心血管细胞群的鉴定。
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2
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Characteristics of intraoperative abnormal hemodynamics during resection of an intra-fourth ventricular tumor located on the dorsal medulla oblongata.
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Functional correlates of activity in neurons projecting from the lamina terminalis to the ventrolateral periaqueductal gray.终纹床核投射到腹外侧水管周围灰质神经元活动的功能相关性。
Eur J Neurosci. 2009 Dec;30(12):2347-55. doi: 10.1111/j.1460-9568.2009.07024.x. Epub 2009 Dec 10.
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Electrical stimulation of the midbrain increases heart rate and arterial blood pressure in awake humans.对中脑进行电刺激会增加清醒人类的心率和动脉血压。
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