Review of the use of marrow transplantation in the treatment of non-Hodgkin's lymphoma.

High-dose chemoradiotherapy followed by marrow transplantation has become a widely used form of therapy for patients with acute leukemia. Because of the success of marrow transplantation in the treatment of this disease, there has been increased interest in the possible application of marrow transplantation to the treatment of other malignancies known to be sensitive to chemotherapy and radiotherapy. In this paper we review the rationale behind the application of marrow transplantation to the treatment of non-Hodgkin's lymphoma and the results that have been achieved to date.