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[B族链球菌的抗生素敏感性]

[Antibiotic sensitivity of Streptococcus group B].

作者信息

Borderon J C, Borderon E, Geslin P, Sissia G, Valla M

出版信息

Pathol Biol (Paris). 1984 Jan;32(1):35-9.

PMID:6366705
Abstract

The minimal inhibitory and bactericidal concentration of 18 antibiotics for 412 isolates of group B streptococci from newborns, mothers or pregnant women were determined. 3.2% of these strains were less susceptible to penicillin G, 1% failed to be inhibited by erythromycin and 1% by chloramphenicol. Antibiotic-killing kinetics was studied with beta-lactams, aminoglycosides, and in combination for 20 isolates. Killing was accelerated by the combination. For these reasons, at least at the beginning of the treatment, the association of ampicillin and an aminoglycoside can be recommended.

摘要

测定了18种抗生素对412株来自新生儿、母亲或孕妇的B族链球菌的最低抑菌浓度和杀菌浓度。这些菌株中有3.2%对青霉素G敏感性较低,1%对红霉素不敏感,1%对氯霉素不敏感。对20株菌株研究了β-内酰胺类、氨基糖苷类抗生素及其联合用药的杀菌动力学。联合用药可加速杀菌。基于这些原因,至少在治疗开始时,推荐氨苄西林和氨基糖苷类联合使用。

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