Furukawa T, Shigematsu H, Aizawa T, Oguchi H, Furuta S
Acta Pathol Jpn. 1983 Nov;33(6):1159-69. doi: 10.1111/j.1440-1827.1983.tb02161.x.
Renal biopsies from 10 patients who had residual symptoms of toxemia of pregnancy were examined by light, electron and immunofluorescent microscopy. The biopsies were performed 1 month to 3 months postpartum. The glomeruli showed a similar lesion, even though to a lesser degree, to that found in toxemia of pregnancy. Subepithelial swellings and endothelial cytoplasmic microtubular structures were also observed. Mesangial and monocyte-like cells contained lysosomes, cholesterol clefts and lipid-containing vacuoles with or without myelin figures, suggesting reparative process in the glomeruli. The present study indicates that the glomerular injury persists for a few months after delivery, together with the concurrent reparative process.
对10例有妊娠中毒症残留症状的患者进行了肾活检，采用光镜、电镜和免疫荧光显微镜检查。活检在产后1个月至3个月进行。肾小球显示出与妊娠中毒症中发现的病变相似的病变，尽管程度较轻。还观察到上皮下肿胀和内皮细胞质微管结构。系膜细胞和单核细胞样细胞含有溶酶体、胆固醇裂隙和含脂质的空泡，有或没有髓鞘样结构，提示肾小球的修复过程。本研究表明，分娩后肾小球损伤持续数月，同时伴有修复过程。
