Viscosity of duodenal juice examined in patients with excretory pancreas insufficiency by the pancreocymin secretin test compared to a control group and patients with cholelithiasis.

The viscosity of duodenal juice obtained during the pancreocymin secretin test from patients with excretory pancreas insufficiency was significantly higher compared to the viscosity of duodenal secretions from a control group or from patients with gall bladder stones. Since the viscosity was inversely related to the total volume as well as the bicarbonate and trypsin concentrations, it is concluded that the increased viscosity is due to a reduction in the secretory activity of the pancreas. The viscosity measurements found for patients with cholelithiasis reflects merely the higher viscosity of the gall bladder bile.