人在分泌素和缩胆囊素-促胰酶素作用下肠激酶的释放
The release of enterokinase following secretin and cholecystokinin-pancreozymin in man.
作者信息
Moss S, Birch G R, Lobley R W, Holmes R
出版信息
Scand J Gastroenterol. 1979;14(8):1001-7.
The release of enterokinase into human duodenal fluid was studied after intravenous injections of secretin and cholecystokinin-pancreozymin (CCK-PZ). In five control subjects there was a significant release of the enzyme after stimulation with either hormone. A similar release of enterokinase was observed after hormonal stimulation in three patients with total biliary obstruction and in four patients with pancreatic exocrine insufficiency. These results suggest that the hormone-mediated release of enterokinase is independent of bile salts and trypsin in man. This release of enterokinase into duodenal fluid may be physiologically important in protein digestion.
在静脉注射促胰液素和胆囊收缩素-促胰酶素（CCK-PZ）后，研究了肠激酶释放到人十二指肠液中的情况。在五名对照受试者中，用任何一种激素刺激后，该酶都有显著释放。在三名完全性胆道梗阻患者和四名胰腺外分泌功能不全患者中，激素刺激后也观察到了类似的肠激酶释放。这些结果表明，在人类中，激素介导的肠激酶释放独立于胆盐和胰蛋白酶。肠激酶释放到十二指肠液中在蛋白质消化中可能具有重要的生理意义。
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