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医院内狂犬病:与角膜移植相关的人类狂犬病病例接触者调查

Nosocomial rabies: investigation of contacts of human rabies cases associated with a corneal transplant.

作者信息

Anderson L J, Williams L P, Layde J B, Dixon F R, Winkler W G

出版信息

Am J Public Health. 1984 Apr;74(4):370-2. doi: 10.2105/ajph.74.4.370.

Abstract

In October 1978 in Boise, Idaho, a woman died of rabies after receiving a corneal transplant from a man, who in retrospect was also found to have died of rabies. Investigation of 203 contacts of these two patients identified 94 who were felt to have had sufficient risk of exposure to justify being given rabies post-exposure prophylaxis. Nurses, physicians, respiratory therapists, and family members were at greatest risk. We discuss the problems encountered in determining risk of exposure for contacts of humans with rabies.

摘要

1978年10月,在爱达荷州博伊西市,一名妇女在接受一名男子的角膜移植后死于狂犬病,事后发现该男子也死于狂犬病。对这两名患者的203名接触者进行调查后,确定其中94人被认为有足够的接触风险,有必要接受狂犬病暴露后预防治疗。护士、医生、呼吸治疗师和家庭成员面临的风险最大。我们讨论了在确定狂犬病患者接触者的接触风险时遇到的问题。

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本文引用的文献

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Human rabies transmitted by corneal transplant.
Arch Neurol. 1982 Feb;39(2):103-7. doi: 10.1001/archneur.1982.00510140037010.
7
Human rabies. Diagnosis, complications, and management.人类狂犬病。诊断、并发症及管理。
Am J Dis Child. 1974 Jun;127(6):862-9. doi: 10.1001/archpedi.1974.02110250088013.
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A model in mice for the pathogenesis and treatment of rabies.
J Infect Dis. 1972 May;125(5):520-7. doi: 10.1093/infdis/125.5.520.

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